{"id":354,"date":"2024-12-22T13:36:15","date_gmt":"2024-12-22T12:36:15","guid":{"rendered":"https:\/\/narya-consulting.fr\/?page_id=354"},"modified":"2025-01-08T09:20:14","modified_gmt":"2025-01-08T08:20:14","slug":"publications","status":"publish","type":"page","link":"https:\/\/narya-consulting.fr\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull has-global-padding is-layout-constrained wp-container-core-group-is-layout-1 wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--40);margin-bottom:var(--wp--preset--spacing--40);padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div style=\"height:0px;width:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-cover is-light has-custom-content-position is-position-top-right is-style-cover-block-link is-style-eccp-cover\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0;min-height:407px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#a98269\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"5366\" height=\"2334\" class=\"wp-block-cover__image-background wp-image-355\" alt=\"\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Bryce-Canyon-8_reduit.jpg\" data-object-fit=\"cover\"\/><div class=\"wp-block-cover__inner-container is-layout-flow wp-container-core-cover-is-layout-1 wp-block-cover-is-layout-flow\">\n<figure class=\"wp-block-image alignleft size-full is-resized has-custom-border is-style-rounded is-style-rounded--1\"><a href=\"https:\/\/www.nature.com\/articles\/nsmb.1544\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"2116\" height=\"912\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Kerrest.jpg\" alt=\"\" class=\"wp-image-861\" style=\"border-radius:15px;width:486px;height:auto\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-resized has-custom-border is-style-rounded is-style-rounded--2\" style=\"margin-top:0;margin-bottom:0\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25743488\/\"><img loading=\"lazy\" decoding=\"async\" width=\"1944\" height=\"654\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2025\/01\/Richard.png\" alt=\"\" class=\"wp-image-1245\" style=\"border-radius:15px;width:580px;height:auto\"\/><\/a><\/figure>\n\n\n\n<p class=\"has-text-align-center has-large-font-size\"><\/p>\n\n\n\n<figure class=\"wp-block-image alignleft size-full is-resized has-custom-border is-style-rounded is-style-rounded--3\"><a href=\"https:\/\/journals.plos.org\/plosgenetics\/article?id=10.1371\/journal.pgen.1008924\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"2918\" height=\"1468\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Mosbach2.jpg\" alt=\"\" class=\"wp-image-863\" style=\"border-radius:15px;width:523px;height:auto\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image alignleft size-full is-resized has-custom-border is-style-rounded is-style-rounded--4\"><a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(18)30147-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124718301475%3Fshowall%3Dtrue\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"1846\" height=\"1512\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Mosbach1.jpg\" alt=\"\" class=\"wp-image-862\" style=\"border-radius:15px;width:397px;height:auto\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-resized has-custom-border is-style-rounded is-style-rounded--5\"><a href=\"https:\/\/www.nature.com\/articles\/nature02579\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"2732\" height=\"983\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Yeast-evolution.jpg\" alt=\"\" class=\"wp-image-880\" style=\"border-radius:15px;width:445px;height:auto\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-resized has-custom-border is-style-rounded is-style-rounded--6\"><a href=\"https:\/\/www.cell.com\/cell-reports\/pdf\/S2211-1247(22)01175-5.pdf\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"1390\" height=\"1144\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Megasat.jpg\" alt=\"\" class=\"wp-image-911\" style=\"border-radius:15px;width:417px;height:auto\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-resized has-custom-border is-style-rounded is-style-rounded--7\"><a href=\"https:\/\/www.nature.com\/articles\/369371a0\" target=\"_blank\" rel=\" noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"2746\" height=\"1286\" src=\"https:\/\/narya-consulting.fr\/wp-content\/uploads\/2024\/12\/Nature-chromXI_bandeau_reduit-1.jpg\" alt=\"\" class=\"wp-image-878\" style=\"border-radius:15px;width:392px;height:auto\"\/><\/a><\/figure>\n<\/div><\/div>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center is-style-default\">MAIN PEER-REVIEWED PUBLICATIONS<\/h1>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-large-font-size\" id=\"genomics\">Genomics<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8196765\/\" target=\"_blank\" rel=\"noreferrer noopener\">Dujon,B., Alexandraki,D., Andr\u00e9,B., Ansorge,W., \u2026 <strong>Guy-Franck Richard<\/strong> <em>et al.<\/em> (1994) Complete DNA sequence of yeast chromosome XI. <em>Nature<\/em>, 369, 371\u2013378.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15229592\/\" target=\"_blank\" rel=\"noreferrer noopener\">Dujon,B., Sherman,D., Fischer,G., Durrens,P., Casaregola,S., Lafontaine,I., <strong>Guy-Franck Richard<\/strong>, <em>et al.<\/em> (2004) Genome evolution in yeasts. <em>Nature<\/em>, 430, 35\u201344.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16177231\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Guy-Franck Richard<\/strong> and Dujon,B. (2006) Molecular evolution of minisatellites in hemiascomycetous yeasts. <em>Mol Biol Evol<\/em>, 23, 189\u2013202.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19052325\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Guy-Franck Richard<\/strong>, Kerrest,A. and Dujon,B. (2008) Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. <em>Microbiol Mol Biol Rev<\/em>, 72, 686\u2013727.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2919712\/\" target=\"_blank\" rel=\"noreferrer noopener\">Rolland,T., Dujon,B. and <strong>Guy-Franck Richard<\/strong> (2010) Dynamic evolution of megasatellites in yeasts. <em>Nucleic Acids Res.<\/em>, 38, 4731\u20134739.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32633916\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Guy-Franck Richard<\/strong> (2020) Eukaryotic Pangenomes. In Tettelin,H., Medini,D. (eds), <em>The Pangenome: Diversity, Dynamics and Evolution of Genomes<\/em>. Springer International Publishing, Cham, pp. 253\u2013291.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36103826\/\" target=\"_blank\" rel=\"noreferrer noopener\">Descorps-Decl\u00e8re,S. and <strong>Guy-Franck Richard<\/strong> (2022) Megasatellite formation and evolution in vertebrate genes. <em>Cell Reports<\/em>, 40, 111347.<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-large-font-size\" id=\"genome-editing\">Genome editing<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10394925\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong>, Dujon,B. and Haber,J.E. (1999) Double-strand break repair can lead to high frequencies of deletions within short CAG\/CTG trinucleotide repeats. <em>Mol Gen Genet<\/em>, 261, 871\u2013882.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24748175\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong>, Viterbo,D., Khanna,V., Mosbach,V., Castelain,L. and Dujon,B. (2014) Highly Specific Contractions of a Single CAG\/CTG Trinucleotide Repeat by TALEN in Yeast. <em>PLOS ONE<\/em>, 9, e95611.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25743488\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong> (2015) Shortening trinucleotide repeats using highly specific endonucleases: a possible approach to gene therapy\u202f? <em>Trends Genetics<\/em>, 31, 177\u2013186.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29466740\/\" target=\"_blank\" rel=\"noreferrer noopener\">Mosbach,V., Poggi,L., Viterbo,D., Charpentier,M. and <strong><strong>Guy-Franck Richard<\/strong><\/strong> (2018) TALEN-induced double-strand break repair of CTG trinucleotide repeats. <em>Cell Reports<\/em>, 22, 2146\u20132159.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29974202\/\" target=\"_blank\" rel=\"noreferrer noopener\">Mosbach,V., Poggi,L. and <strong><strong>Guy-Franck Richard<\/strong> <\/strong>(2018) Trinucleotide repeat instability during double-strand break repair: from mechanisms to gene therapy. <em>Curr. Genet.<\/em>, 10.1007\/s00294-018-0865-1.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7413560\/\" target=\"_blank\" rel=\"noreferrer noopener\">Mosbach,V., Viterbo,D., Descorps-Decl\u00e8re,S., Poggi,L., Vaysse-Zinkh\u00f6fer,W. and <strong><strong>Guy-Franck Richard<\/strong><\/strong> (2020) Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions. <em>PLOS Genetics<\/em>, 16, e1008924.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34233005\/\" target=\"_blank\" rel=\"noreferrer noopener\">Poggi,L., Emmenegger,L., Descorps-Decl\u00e8re,S., Dumas,B. and <strong><strong>Guy-Franck Richard<\/strong><\/strong> (2021) Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations. <em>Nucleic Acids Research<\/em>, 49, 8120\u20138134.<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-large-font-size\" id=\"microsatellite-expansions\">Microsatellite expansions<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10811629\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Guy-Franck Richard<\/strong>, Goellner,G.M., McMurray,C.T. and Haber,J.E. (2000) Recombination-induced CAG trinucleotide repeat expansions in yeast involve the <em>MRE11<\/em>\/<em>RAD50<\/em>\/<em>XRS2<\/em> complex. <em>EMBO J<\/em>, 19, 2381\u20132390.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11265750\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong> and P\u00e2ques,F. (2000) Mini- and microsatellite expansions: the recombination connection. <em>EMBO Rep.<\/em>, 1, 122\u2013126.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11158105\/\" target=\"_blank\" rel=\"noreferrer noopener\">Hennequin,C., Thierry,A., <strong><strong>Guy-Franck Richard<\/strong><\/strong>, Lecointre,G., Nguyen,H.V., Gaillardin,C. and Dujon,B. (2001) Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains. <em>J Clin. Microbiol.<\/em>, 39, 551\u2013559.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11333226\/\" target=\"_blank\" rel=\"noreferrer noopener\">P\u00e2ques,F., <strong><strong>Guy-Franck Richard<\/strong><\/strong> and Haber,J.E. (2001) Expansions and contractions in 36-bp minisatellites by gene conversion in yeast. <em>Genetics<\/em>, 158, 155\u2013166.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12581639\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong>, Cyncynatus,C. and Dujon,B. (2003) Contractions and expansions of CAG\/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a <em>MUS81<\/em>-independent mechanism. <em>J. Mol. Biol.<\/em>, 326, 769\u2013782.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4454460\/\" target=\"_blank\" rel=\"noreferrer noopener\">Kerrest,A., Anand,R., Sundararajan,R., Bermejo,R., Liberi,G., Dujon,B., Freudenreich,C.H. and <strong><strong>Guy-Franck Richard<\/strong><\/strong> (2009) <em>SRS2<\/em> and <em>SGS1<\/em> prevent chromosomal breaks and stabilize triplet repeats by restraining recombination. <em>Nat. Struct. Mol. Biol.<\/em>, 16, 159\u2013167.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27045900\/\" target=\"_blank\" rel=\"noreferrer noopener\">Viterbo,D., Michoud,G., Mosbach,V., Dujon,B. and <strong><strong>Guy-Franck Richard<\/strong><\/strong> (2016) Replication stalling and heteroduplex formation within CAG\/CTG trinucleotide repeats by mismatch repair. <em>DNA Repair<\/em>, 42, 94\u2013106.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28175398\/\" target=\"_blank\" rel=\"noreferrer noopener\">Nguyen,J.H.G., Viterbo,D., Anand,R.P., Verra,L., Sloan,L., <strong><strong>Guy-Franck Richard<\/strong><\/strong> and Freudenreich,C.H. (2017) Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG\/CTG repeats. <em>Nucleic Acids Research<\/em>, 45, 4519\u20134531.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-022-01456-3\" target=\"_blank\" rel=\"noreferrer noopener\">Vertti-Quintero,N., Levien,E., Poggi,L., Amir,A.,<strong>Guy-Franck Richard<\/strong> and Baroud,C.N. (2022) Time-resolved microfluidics unravels individual cellular fates during double-strand break repair. <em>BMC Biol.<\/em>, 20, 269.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33925919\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><strong>Guy-Franck Richard<\/strong><\/strong> (2021) The Startling Role of Mismatch Repair in Trinucleotide Repeat Expansions. <em>Cells<\/em>, 10, 1019.<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<!-- Google Tag Manager -->\n<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':\nnew Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],\nj=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=\n'https:\/\/www.googletagmanager.com\/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);\n})(window,document,'script','dataLayer','GTM-W39K8TNM');<\/script>\n<!-- End Google Tag Manager -->\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\" id=\"the-complete-list-of-publications-may-be-consulted-here\">The complete list of publications may be consulted <strong><a href=\"https:\/\/scholar.google.fr\/citations?hl=fr&amp;user=-SOW6_DheSEC\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a><\/strong><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>MAIN PEER-REVIEWED PUBLICATIONS Genomics Genome editing Microsatellite expansions The complete list of publications may be consulted here<\/p>\n","protected":false},"author":1,"featured_media":355,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"remove_blocks_before_content":false,"remove_blocks_after_content":false,"disable_reading_progress_bar":false,"footnotes":""},"class_list":["post-354","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/pages\/354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/comments?post=354"}],"version-history":[{"count":119,"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/pages\/354\/revisions"}],"predecessor-version":[{"id":1265,"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/pages\/354\/revisions\/1265"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/media\/355"}],"wp:attachment":[{"href":"https:\/\/narya-consulting.fr\/index.php\/wp-json\/wp\/v2\/media?parent=354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}