MAIN PEER-REVIEWED PUBLICATIONS
Genomics
- Dujon,B., Alexandraki,D., André,B., Ansorge,W., … Guy-Franck Richard et al. (1994) Complete DNA sequence of yeast chromosome XI. Nature, 369, 371–378.
- Dujon,B., Sherman,D., Fischer,G., Durrens,P., Casaregola,S., Lafontaine,I., Guy-Franck Richard, et al. (2004) Genome evolution in yeasts. Nature, 430, 35–44.
- Guy-Franck Richard and Dujon,B. (2006) Molecular evolution of minisatellites in hemiascomycetous yeasts. Mol Biol Evol, 23, 189–202.
- Guy-Franck Richard, Kerrest,A. and Dujon,B. (2008) Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. Microbiol Mol Biol Rev, 72, 686–727.
- Rolland,T., Dujon,B. and Guy-Franck Richard (2010) Dynamic evolution of megasatellites in yeasts. Nucleic Acids Res., 38, 4731–4739.
- Guy-Franck Richard (2020) Eukaryotic Pangenomes. In Tettelin,H., Medini,D. (eds), The Pangenome: Diversity, Dynamics and Evolution of Genomes. Springer International Publishing, Cham, pp. 253–291.
- Descorps-Declère,S. and Guy-Franck Richard (2022) Megasatellite formation and evolution in vertebrate genes. Cell Reports, 40, 111347.
Genome editing
- Guy-Franck Richard, Dujon,B. and Haber,J.E. (1999) Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats. Mol Gen Genet, 261, 871–882.
- Guy-Franck Richard, Viterbo,D., Khanna,V., Mosbach,V., Castelain,L. and Dujon,B. (2014) Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast. PLOS ONE, 9, e95611.
- Guy-Franck Richard (2015) Shortening trinucleotide repeats using highly specific endonucleases: a possible approach to gene therapy ? Trends Genetics, 31, 177–186.
- Mosbach,V., Poggi,L., Viterbo,D., Charpentier,M. and Guy-Franck Richard (2018) TALEN-induced double-strand break repair of CTG trinucleotide repeats. Cell Reports, 22, 2146–2159.
- Mosbach,V., Poggi,L. and Guy-Franck Richard (2018) Trinucleotide repeat instability during double-strand break repair: from mechanisms to gene therapy. Curr. Genet., 10.1007/s00294-018-0865-1.
- Mosbach,V., Viterbo,D., Descorps-Declère,S., Poggi,L., Vaysse-Zinkhöfer,W. and Guy-Franck Richard (2020) Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions. PLOS Genetics, 16, e1008924.
- Poggi,L., Emmenegger,L., Descorps-Declère,S., Dumas,B. and Guy-Franck Richard (2021) Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations. Nucleic Acids Research, 49, 8120–8134.
Microsatellite expansions
- Guy-Franck Richard, Goellner,G.M., McMurray,C.T. and Haber,J.E. (2000) Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11/RAD50/XRS2 complex. EMBO J, 19, 2381–2390.
- Guy-Franck Richard and Pâques,F. (2000) Mini- and microsatellite expansions: the recombination connection. EMBO Rep., 1, 122–126.
- Hennequin,C., Thierry,A., Guy-Franck Richard, Lecointre,G., Nguyen,H.V., Gaillardin,C. and Dujon,B. (2001) Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains. J Clin. Microbiol., 39, 551–559.
- Pâques,F., Guy-Franck Richard and Haber,J.E. (2001) Expansions and contractions in 36-bp minisatellites by gene conversion in yeast. Genetics, 158, 155–166.
- Guy-Franck Richard, Cyncynatus,C. and Dujon,B. (2003) Contractions and expansions of CAG/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a MUS81-independent mechanism. J. Mol. Biol., 326, 769–782.
- Kerrest,A., Anand,R., Sundararajan,R., Bermejo,R., Liberi,G., Dujon,B., Freudenreich,C.H. and Guy-Franck Richard (2009) SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination. Nat. Struct. Mol. Biol., 16, 159–167.
- Viterbo,D., Michoud,G., Mosbach,V., Dujon,B. and Guy-Franck Richard (2016) Replication stalling and heteroduplex formation within CAG/CTG trinucleotide repeats by mismatch repair. DNA Repair, 42, 94–106.
- Nguyen,J.H.G., Viterbo,D., Anand,R.P., Verra,L., Sloan,L., Guy-Franck Richard and Freudenreich,C.H. (2017) Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats. Nucleic Acids Research, 45, 4519–4531.
- Vertti-Quintero,N., Levien,E., Poggi,L., Amir,A.,Guy-Franck Richard and Baroud,C.N. (2022) Time-resolved microfluidics unravels individual cellular fates during double-strand break repair. BMC Biol., 20, 269.
- Guy-Franck Richard (2021) The Startling Role of Mismatch Repair in Trinucleotide Repeat Expansions. Cells, 10, 1019.
